Arrowhead reports interim Phase 1/2a ARO-MAPT data
The company says clinical data in healthy volunteers demonstrated deep and durable tau reductions.
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The company says clinical data in healthy volunteers demonstrated deep and durable tau reductions.
For best results when printing this announcement, please click on link below: Arrowhead Pharmaceuticals Announces ARO-MAPT Interim Phase 1/2a Clinical Data Demonstrating Deep and Durable Tau Reductions in Healthy Volunteers Arrowhead’s TRiM(™) platform achieves clinical validation for delivery of siRNA that crosses the
Interim data showed subcutaneous ARO-MAPT reduced CSF total tau by a mean of up to 73% at Day 105, with a maximum reduction of 85%, in healthy volunteers. The drug was generally well tolerated.
Arrowhead Pharmaceuticals announced interim results from an ongoing Phase 1/2a study of its investigational RNAi therapy ARO-MAPT, reporting deep and durable tau reductions in healthy volunteers.
The webinar is scheduled for Wednesday, October 14, 2026 at 11:30 AM PDT and will focus on investigational therapy ARO-MAPT and Arrowhead's CNS pipeline. It will include interim results from the Phase 1/2a AROMAPT-SC-1001 study.