aTyr Pharma reports Journal of Biological Chemistry paper showing anti — fibrotic effects of ATYR0101 in lung model
aTyr Pharma published Journal of Biological Chemistry data showing anti-fibrotic activity for ATYR0101, a DARS-derived fusion protein. Mechanism targets LTBP-1 to trigger myofibroblast apoptosis, with activity dependent on active TGF-β. In a bleomycin lung fibrosis model, ATYR0101 reduced collagen content and Ashcroft