AngioDynamics Announces Humana Medicare Advantage Coverage Policy Supporting Broader Access to NanoKnife® IRE for Prostate and Liver Cancer

For best results when printing this announcement, please click on link below: AngioDynamics Announces Humana Medicare Advantage Coverage Policy Supporting Broader Access to NanoKnife(®) IRE for Prostate and Liver Cancer Policy Applies Medical Necessity Criteria Across Medicare Administrative Contractor (MAC) Jurisdictions for Eligible Prostate and Liver Cancer Patients AngioDynamics, Inc. (2) Coverage remains subject to Humana’s prior authorization process and the terms of each member’s plan.

(1) “Humana’s decision is an important step toward more consistent access to NanoKnife IRE for eligible patients,” said Juan Carlos Serna, AngioDynamics Senior Vice President of Scientific and Clinical Affairs. ” “For men with favorable intermediate-risk prostate cancer, the choice often comes down to observing their cancer with active surveillance or undergoing radical treatments with potential side effects of therapy,” said Xiaosong Meng, MD, PhD, of the Department of Urology at UT Southwestern Medical Center.

“Focal therapies such as IRE give us another option for men with intermediate-risk prostate cancer while working to protect the structures that matter to a patient's quality of life. ” Dr. Meng is a paid consultant to AngioDynamics. For complete coverage criteria and clinical requirements refer to Policy No.

HUM-1268-005 and LCD L40205. About the NanoKnife System The NanoKnife System utilizes Irreversible Electroporation (IRE) technology to effectively destroy targeted cells without the use of thermal energy by delivering high-voltage electrical pulses, creating permanent nanopores within the cell membrane. com for full product information. United States: The NanoKnife System with six outputs is indicated for surgical ablation of soft tissue, including prostate tissue.

Canada: The NanoKnife System is a medical device for cell membrane electroporation. Electroporation is a phenomenon that occurs in cell membranes as cells are exposed to an electrical field of sufficiently high intensity. The electric field acts as a physical stimulus, bringing about alterations in cell membranes that result in increased permeability. European Union: The NanoKnife System is indicated for the ablation of soft tissue and tumors of the pancreas, kidney, liver, or prostate, including intermediate risk prostate cancer.

About AngioDynamics, Inc. AngioDynamics is a leading and transformative medical technology company focused on restoring healthy blood flow in the body's vascular system, expanding cancer treatment options, and improving quality of life for patients. The Company's innovative technologies and devices are chosen by talented physicians in fast-growing healthcare markets to treat unmet patient needs. com Safe Harbor This release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995.

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AngioDynamics does not assume any obligation to publicly update or revise any forward-looking statements for any reason. , an affiliate or subsidiary. All other trademarks are property of their respective owners. ______________________ (1) Humana.

Irreversible Electroporation. Medicare Advantage Medical Coverage Policy. Policy No. HUM-1268-005.

Effective October 1, 2026. (2) KFF. Medicare Advantage in 2026: Enrollment Update and Key Trends. June 5, 2026; updated July 1, 2026.

(3) Lee EW, Thai S, Kee ST. Irreversible electroporation: a novel image-guided cancer therapy. Gut Liver. 2010;4 Suppl 1(Suppl 1):S99-S104.

com: Investors: AngioDynamics, Inc. com)