Johnson & Johnson reports Q3 2026 results, raises 2026 guidance

9% at the midpoint Significant innovation including the market authorization of OTTAVA as the world’s first table-integrated soft tissue robotic system, approval of IMAAVY in warm autoimmune hemolytic anemia (wAIHA), and priority review for RYBREVANT FASPRO for advanced head and neck cancer Johnson & Johnson (NYSE: JNJ) today announced results for third-quarter 2026. “Johnson & Johnson’s strong third-quarter performance and increased sequential growth reflect the accelerating momentum of our focused portfolio,” said Joaquin Duato, Chairman and Chief Executive Officer.

“In the third quarter, we advanced breakthroughs that will redefine care for patients, from delivering one of our most transformative MedTech innovations with OTTAVA to reporting positive Phase 3 results in multiple myeloma.

5)% Free Cash Flow(5,6) ~$15,100 $14,226 (1) Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules (2) Excludes the impact of translational currency (3) Excludes the net impact of acquisitions and divestitures and translational currency (4) Excludes intangible amortization expense and special items (5) Non-GAAP financial measure; defined as cash flow from operating activities, less additions to property, plant and equipment. Cash flow from operations, the most directly comparable GAAP financial measure, will be included in subsequent SEC filings. S.

1 (1) Non-GAAP financial measure; refer to reconciliations of non-GAAP financial measures included in accompanying schedules (2) Excludes the impact of translational currency (3) Excludes the net impact of acquisitions and divestitures and translational currency Note: values may have been rounded Third-Quarter 2026 segment commentary: Operational sales* reflected below excludes the impact of translational currency. 9%*, with divestitures negatively impacting growth by 10 basis points.

Growth was primarily driven by TREMFYA and new products within Other in Immunology, DARZALEX, CARVYKTI, TECVAYLI, RYBREVANT/LAZCLUZE, and ERLEADA in Oncology, and SPRAVATO and CAPLYTA in Neuroscience. Growth was partially offset by STELARA (an approximate 690 basis points impact), SIMPONI/SIMPONI ARIA, and REMICADE in Immunology, as well as OPSUMIT/OPSYNVI in Pulmonary Hypertension, and IMBRUVICA in Oncology. 5%*. Growth was primarily driven by electrophysiology products and Shockwave in Cardiovascular, contact lenses in Vision, as well as trauma in Orthopaedics.

Full-year 2026 guidance: Johnson & Johnson does not provide GAAP financial measures on a forward-looking basis because the company is unable to predict with reasonable certainty the ultimate outcome of legal proceedings, unusual gains and losses, acquisition-related expenses, and purchase accounting fair value adjustments without unreasonable effort. These items are uncertain, depend on various factors, and could be material to Johnson & Johnson's results computed in accordance with GAAP. 5% Change vs. 6B Change vs.

1B Change vs. 94 Change vs. 04 Change vs. 15 (Illustrative purposes only) (4) Non-GAAP financial measure; excludes intangible amortization expense and special items Note: percentages may have been rounded Other modeling considerations will be provided on the webcast.

Notable announcements in the quarter: The information contained in this section should be read together with Johnson & Johnson’s other disclosures filed with the Securities and Exchange Commission, including its Current Reports on Form 8-K, Quarterly Reports on Form 10-Q and Annual Reports on Form 10-K. Copies of these filings are available online at ( ), or on request from Johnson & Johnson. S. S.

for its Press Release OTTAVA™ Robotic Surgical System Johnson & Johnson Announces MONARCH™ QUEST 3, Advancing the Latest in Press Release Robotically-Assisted Bronchoscopy Data Releases New Johnson & Johnson ICOTYDE(®) (icotrokinra) long-term data demonstrate Press Release robust 2- year results in the treatment of adults and adolescents with plaque psoriasis(1) Johnson & Johnson announces new ICOTYDE™ (icotrokinra) data in Press Release difficult-to-treat plaque psoriasis with proven durability through 2-years, affirming its use as a powerful first line systemic therapy(1) Johnson & Johnson presents new data reinforcing sustained disease control Press Release and improved daily function achieved with IMAAVY(®) (nipocalimab-aahu) in generalized myasthenia gravis (gMG) Johnson & Johnson announces TREMFYA(®) (guselkumab) is the first and only Press Release IL-23 inhibitor to show significant improvement in spinal pain and stiffness in landmark axial psoriatic arthritis (PsA) study Single infusion of CARVYKTI(®) (ciltacabtagene autoleucel) delivered Press Release five-year treatment-free remissions in 50% of patients in early line relapsed/refractory multiple myeloma New model-based analysis further supports the potential of TECVAYLI(®) Press Release (teclistamab-cqyv) plus DARZALEX FASPRO(®) (daratumumab and hyaluronidase-hj) to redene long-term survival expectations in early line relapsed/refractory multiple myeloma CAPLYTA(®) (lumateperone) shows significant and rapid improvement in bipolar Press Release mania in pivotal Phase 3 study RYBREVANT FASPRO™ (amivantamab and hyaluronidase-lpuj) plus LAZCLUZE(®) Press Release (lazertinib) with prophylactic strategies shows low rates of treatment-related events at WCLC 2026 Johnson & Johnson's RYBREVANT(®) (amivantamab-vmjw) plus chemotherapy Press Release delivers longest reported median overall survival in EGFR exon 20 insertion mutation-positive lung cancer Johnson & Johnson spotlights new neuropsychiatry data across bipolar Press Release mania, depression and schizophrenia at Psych Congress 2026 TECVAYLI(®) + TALVEY(®) reduced the risk of disease progression or death by Press Release 89% and the risk of death by 62% in earlier-line relapsed/refractory multiple myeloma Other New Global Survey by Johnson & Johnson Finds Most Women Don’t Connect Press Release Eye Health Changes with Menopause(1) Johnson & Johnson’s Executive Vice President Jennifer Taubert to Retire; Press Release Tom Cavanaugh Appointed EVP, Worldwide Chairman Innovative Medicine Effective September Johnson & Johnson Completes Acquisition of Firefly Bio, Inc.

, Eastern Time. A simultaneous webcast of the call for investors and other interested parties may be accessed by visiting the Johnson & Johnson website. A replay and podcast will be available approximately two hours after the live webcast in the Investor Relations section of the company's website at events-and-presentations About Johnson & Johnson: At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.

Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.

Learn more at Non-GAAP financial measures: “Operational sales growth” excluding the impact of translational currency, “adjusted operational sales growth” excluding the net impact of acquisitions and divestitures and translational currency, as well as “adjusted net earnings”, “adjusted diluted earnings per share” and “adjusted operational diluted earnings per share” excluding after-tax intangible amortization expense and special items, are non-GAAP financial measures and should not be considered replacements for, and should be read together with, the most comparable GAAP financial measures.

Except for guidance measures, reconciliations of these non-GAAP financial measures to the most directly comparable GAAP financial measures can be found in the accompanying financial schedules of the earnings release and the Investor Relations section of the company's website at quarterly results Copies of the financial schedules accompanying this earnings release are available on the company’s website at quarterly results ( ). These schedules include supplementary sales data, a condensed consolidated statement of earnings, reconciliations of non-GAAP financial measures, and sales of key products/franchises.

Additional information on Johnson & Johnson, including adjusted income before tax by segment, an Innovative Medicine pipeline of selected compounds in late stage development and a copy of today’s earnings call presentation can also be found in the Investor Relations section of the company's website at quarterly results Note to investors concerning forward-looking statements: This press release contains “forward-looking statements” as defined in the Private Securities Litigation Reform Act of 1995 regarding, among other things: future operating and financial performance, product development, and market position and business strategy.

The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of Johnson & Johnson.

Risks and uncertainties include, but are not limited to: economic factors, such as interest rate and currency exchange rate fluctuations or changes to applicable laws and regulations; competition, including technological advances, new products and patents attained by competitors; challenges inherent in new product research and development, including uncertainty of clinical success and obtaining regulatory approvals; uncertainty of commercial success for new and existing products; challenges to patents; the impact of patent expirations; the ability of the Company to successfully execute strategic plans, including restructuring plans; the impact of business combinations and divestitures; manufacturing difficulties or delays, internally or within the supply chain; product efficacy or safety concerns resulting in product recalls or regulatory action; significant adverse litigation or government action, including related to product liability claims; changes to applicable laws and regulations, including tax laws and global health care reforms; trends toward health care cost containment; changes in behavior and spending patterns of purchasers of health care products and services; financial instability of international economies and legal systems and sovereign risk; increased scrutiny of the health care industry by government agencies; and the Company's ability to successfully separate the Company's Orthopaedics business and realize the anticipated benefits from the planned separation.

A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson’s most recent Annual Report on Form 10-K, including in the sections captioned “Cautionary Note Regarding Forward-Looking Statements” and “Item 1A. Risk Factors,” and in Johnson & Johnson’s subsequent Quarterly Reports on Form 10-Q and other filings with the Securities and Exchange Commission. com ( ), or on request from Johnson & Johnson. Any forward-looking statement made in this release speaks only as of the date of this release.

Johnson & Johnson does not undertake to update any forward-looking statement as a result of new information or future events or developments. S. S. S.

4 Note: Percentages have been calculated using actual, non-rounded figures and, therefore, may not recalculate precisely. S. S.