Curatis reports record first half with 51% revenue jump, advances drug candidate

Curatis Holding AG / Key word(s): Half Year Results Strongest half-year in Curatis’s history — revenue up 51% and significant progress on corticorelin (C-PTBE-01) 21-Sep-2026 / 07:00 CET/CEST Release of an ad hoc announcement pursuant to Art. 53 LR The issuer is solely responsible for the content of this announcement. ══════════════════════════════════════════════════════════════════════════ Ad hoc announcement pursuant to Art. 9m).

Curatis also advanced its corticorelin (C-PTBE-01) program on multiple levels, including an exclusive Japan licence with Neupharma and continued manufacturing progress. 2m). Growth was driven both by products marketed for some time and by products added to the distribution portfolio in 2025 and 2026. 5m).

4%. 4m, reflecting capitalised development expenditure. In CHF thousand unless noted H1 2026 H1 2025 Change Net sales from goods and services (kCHF) 7'940 5'243 51% of which net sales from goods 7'373 5'038 46% of which net sales from services 567 205 ----- Gross contribution from goods and services (kCHF) 1'707 1'292 32% Operating result (kCHF) -401 -1'291 69% Cash and cash equivalents (kCHF) 3'595¹ 1'867² 92% ¹ 30 June 2026. ² 31 December 2025.

For a more detailed discussion, please refer to the half-year report and management discussion and analysis available at Corticorelin / C-PTBE-01 Curatis’ lead product candidate, C-PTBE-01 (corticorelin), is being developed to treat peritumoral brain edema (PTBE), affecting more than 150’000 patients in the US alone, for which the current standard of care, corticosteroids, causes significant side effects and can counteract cancer immunotherapies. Corticorelin is an investigational drug not yet approved for therapeutic use in the United States or elsewhere. Curatis advanced the corticorelin program on several levels in the first half of 2026.

5m in upfront and milestone payments plus royalties of up to 20% — Curatis’ first regional partnership for the program. As planned, Neupharma met with Japan’s health authority, PMDA, to discuss possible development pathways for that market. On the manufacturing side, Curatis received several API batches at a higher yield than expected, the technical development for the drug product is on schedule and a cell-based potency assay is on track for validation by year-end. Corticorelin, unlike chronic corticosteroid use, may leave immune function intact.

Curatis is actively pursuing this attractive additional field of application for the compound. 8m), resulting in a revenue growth of approximately 40% in 2026. The Group’s objective remains a break-even result in 2026. Curatis plans to meet the FDA in the first quarter of 2027 to finalise the pivotal Phase 3 study design for corticorelin, following the study design discussed with the FDA in September 2025.

During 2027, the company expects to complete production of clinical study material and prepare for the study with a contract research organization, including selection of study centers. SW) specializing in the late stage development and commercialization of drugs for rare diseases and specialty care. Curatis has a sales portfolio of 50 products and a pipeline of orphan and specialty drugs. com Disclaimer The information contained in this media release and in any link to our website indicated herein is not for use within any country or jurisdiction or by any persons where such use would constitute a violation of law.

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══════════════════════════════════════════════════════════════════════════ End of Inside Information ══════════════════════════════════════════════════════════════════════════ Language: English Company: Curatis Holding AG Weierweg 7 4410 Liestal Switzerland ISIN: CH1330780979 Listed: SIX Swiss Exchange EQS News ID: 2401910 End of Announcement EQS News Service 2401910 21-Sep-2026 CET/CEST References Visible links 1. com