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Zipalertinib plus chemotherapy improves PFS in REZILIENT-3

Phase III REZILIENT-3 reports median progression-free survival of 14.5 months with zipalertinib plus chemotherapy versus 8.5 months with chemotherapy alone in first-line EGFR exon 20 insertion mutation NSCLC, with CNS efficacy in brain metastases and manageable safety.

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