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ProMIS Neurosciences Phase 1b data show zero ARIA and p-tau217 reduction

Interim Phase 1b Alzheimer’s trial data for a novel antibody platform targeting misfolded proteins report zero ARIA cases and a significant p-tau217 reduction. Top-line results are expected in Q1 2027.

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ProMIS Neurosciences said its novel antibody platform targeting misfolded proteins in neurodegenerative diseases showed strong interim safety and promising biomarker signals in a Phase 1b Alzheimer’s trial. The company reported zero ARIA cases and significant p-tau217 reduction. Top-line results are expected in Q1 2027.