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Spyre says Phase 2 SKYLINE Part A met primary endpoint

Spyre said SPY003 met the primary endpoint in Phase 2 SKYLINE Part A, with a 10.0-point RHI reduction at Week 12 and supportive remission and endoscopic improvements. Part B is enrolling, with topline in 2027.

SYRE

Key Highlights:Original SEC Filing: Spyre Therapeutics, Inc. [ SYRE ] - 8-K - Sep. 08, 2026This is an AI-powered summary. It may contain inaccuracies…