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Novartis announces pelacarsen Lp(a)HORIZON Phase 3 topline: primary endpoint missed

Novartis announced pelacarsen Phase 3 Lp(a)HORIZON topline results. The study did not meet its primary endpoint to reduce the risk of cardiovascular events, a composite including cardiovascular death and non-fatal myo…

IONS

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) partner Novartis today announced that the pelacarsen Phase 3 Lp(a)HORIZON study, a pioneering cardiovascular outcomes trial, did not meet its primary endpoint of reducing the risk of cardiovascular events, a composite of cardiovascular death, non-fatal myo…